The will take on the at 1 p.m. ET on Sunday at Lucas Oil Stadium. The Rams rolled to a 34-14 road https://www.royalsgearonestop.com/kansas-city-royals-jersey/bo-jackson-jersey victory in their season opener vs. the . The Colts took a 28-16 home lo s to the in Week 1.The Rams have won the last two meetings between the teams. Los Angeles is favored by 3.5 points in the latest Colts vs. Rams odds from Caesars Sportsbook, and the over-under is set at 48. Before entering any Rams vs. Colts picks, The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 2 of https://www.royalsgearonestop.com/kansas-city-royals-jersey/michael-saunders-jersey the 2021 season on an incredible 121-79 run on top-rated that dates back to the 2017 season. The model also ranked in the Top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP Now, the model has set its sights on . . Here are several for Rams vs. Colts:Colts vs. Rams spread: Rams -3.5Colts vs. Rams over-under: 48 points Featured Game | Indianapolis Colts vs. Los Angeles Rams Moneyline Spread Total IND LAR What you need to know about the Rams pa sed for three TDs and 321 yards on 26 attempts in his Rams debut vs. the Bears. He threw a 67-yard TD pa s to in the first quarter. Stafford finished the game https://www.royalsgearonestop.com/kansas-city-royals-jersey/frank-white-jersey with a career-high 156.1 rating. He has 300-plus yards with two-plus TD pa ses in his last three matchups with the Colts. finished with seven catches for 108 yards last week, his 12th-career 100 yard game, and he scored his 25th career receiving TD. Kupp had five-plus receptions in seven of eight road games last season. had nine sacks and three forced fumbles in eight road games last year. What you need to know about the Colts pa sed for two TDs and 251 yards on https://www.royalsgearonestop.com/kansas-city-royals-jersey/jason-vargas-jersey 38 attempts in his Colts debut vs. Seattle. caught both TD pa ses and has scored in three of his past four games. WRs Jr. (ankle) and (abdomen) are listed as questionable for Week 2.Tackle (foot) and cornerback (calf) have been ruled out for Sunday's game. had a career-high six receptions and 116 scrimmage https://www.royalsgearonestop.com/kansas-city-royals-jersey/burch-smith-jersey yards vs. the Seahawks. had 82 scrimmage yards.How to make Rams vs. Colts picksThe model has simulated Colts vs. Rams 10,000 times and the results are in. The model is leaning under on the total, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. .So who wins Rams vs. Colts? And which side of the spread hits more than 50 percent of the time?.